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Screening for bacteriuria in Japanese school children
1Department of Pediatrics, Kitasato University School of Medicine, Japan.
Insights
Bacteriuria, a urinary tract infection, was screened in over 28,000 children. Persistent bacteriuria was found in 60% of cases, with urinary tract anomalies detected in some children.
Area of Science:
- Pediatrics
- Urology
- Microbiology
Background:
- Bacteriuria, the presence of bacteria in urine, is a common concern in pediatric populations.
- Screening for bacteriuria is crucial for early detection and management of potential urinary tract issues.
- Accurate diagnostic methods are essential for reliable bacteriuria screening in children.
Purpose of the Study:
- To screen a large cohort of healthy school children for bacteriuria.
- To evaluate the prevalence of bacteriuria in boys and girls.
- To assess the accuracy of dipstick and dipslide methods compared to pour plate culture and identify persistent cases.
Main Methods:
- A large-scale screening of 28,202 healthy school children (14,575 boys, 13,627 girls) was conducted.
- Urine samples were analyzed using dipstick, dipslide (Microstix-3), and pour plate culture methods.
- Persistent bacteriuria was monitored through monthly urine cultures for 9 months post-screening.
Main Results:
- The prevalence of bacteriuria was 0.06% in boys and 0.52% in girls after the third screening.
- Dipstick tests showed a high rate of false negatives, while dipslide methods yielded a high rate of false positives.
- Approximately 60% of children with initial bacteriuria showed persistent infection over 9 months.
- Urinary tract anomalies were identified in 9 out of 26 children with persistent bacteriuria.
Conclusions:
- Bacteriuria screening in school children revealed a higher prevalence in girls.
- Diagnostic limitations exist with dipstick and dipslide methods, necessitating careful interpretation.
- Persistent bacteriuria is common and associated with urinary tract anomalies, underscoring the need for follow-up and further investigation.
Abstract:
Bacteriuria was screened among 28,202 healthy school children, 14,575 boys and 13,627 girls, by dipstick and dipslide methods and also by pour plate culture. The prevalence of bacteriuria was 0.06% in boys and 0.52% in girls after the third screening. A high rate of false negative results with the dipstick test and a high rate of false positive results with the dipslide culture method using Microstix-3 were observed. About 60% of screened children continued to have bacteriuria persistently for 9 months after the third screening, which was followed by monthly urine cultures. Anomalies of the urinary tract were detected in 9 of 26 children with persistent bacteriuria.