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Retrograde Perfusion and Filling of Mouse Coronary Vasculature as Preparation for Micro Computed Tomography Imaging

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Published on: February 10, 2012

Noninvasive imaging techniques of constrictive pericarditis.

Ronald Mastouri¹, Stephen G Sawada, Jo Mahenthiran

¹Department of Medicine of Indiana University Medical Center and the Krannert Institute of Cardiology, Indianapolis, IN, USA.

Expert Review of Cardiovascular Therapy

|September 11, 2010

Summary

Constrictive pericarditis (CP) involves pericardial scarring that impedes heart filling, often presenting as right heart failure. Diagnosis relies on imaging, frequently requiring a multimodality approach for confirmation.

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Retrograde Perfusion and Filling of Mouse Coronary Vasculature as Preparation for Micro Computed Tomography Imaging

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Published on: February 10, 2012

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 9, 2010

Area of Science:

Cardiology
Medical Imaging

Background:

Constrictive pericarditis (CP) stems from pericardial scarring, restricting cardiac filling and leading to right heart failure symptoms.
It can arise secondary to various pericardial diseases.

Purpose of the Study:

To summarize the diagnostic approaches for constrictive pericarditis.
To highlight the roles of different imaging modalities in diagnosing CP.

Main Methods:

Review of echocardiography as the initial diagnostic tool.
Inclusion of computed tomography (CT) and cardiac magnetic resonance (CMR) imaging.
Discussion of the multimodality imaging approach.

Main Results:

Echocardiography is the first-line imaging for CP but lacks pathognomonic signs.
CT effectively visualizes pericardial thickening and calcification.
CMR offers comprehensive assessment of the pericardium, myocardium, and cardiac function.

Conclusions:

Diagnosing CP often necessitates a combination of imaging techniques.
Multimodality imaging, integrating echocardiography, CT, and CMR, is crucial for conclusive diagnosis.