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[Effect of psychotropic preparations on cyclic AMP phosphodiesterase activity in the rat cerebral cortex]

T G Shchekoldina, O E Vatolkina, R E Libinzon

Voprosy Meditsinskoi Khimii

|March 1, 1978

Abstract:

Effect of various psychotropic preparations on cAMP phosphodiesterase was studied. Almost all the psychotropic drugs studied were shown to inhibit the enzymatic activity. Neuroleptics--derivatives of phenothiazine and butyrophene--caused the strongest inhibitory effect.

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