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Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice
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CD56 negative NK cells: origin, function, and role in chronic viral disease

Niklas K Björkström1, Hans-Gustaf Ljunggren, Johan K Sandberg

  • 1Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, S-141 86 Stockholm, Sweden. niklas.bjorkstrom@ki.se

Trends in Immunology
|September 11, 2010
PubMed
Summary

Aberrant CD56 negative (CD56neg) Natural Killer (NK) cells accumulate in chronic HIV-1 and Hepatitis C Virus (HCV) infections. This NK cell subset may impair host immunity during long-term viral infections.

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