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Updated: Jun 8, 2026

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Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
Published on: December 1, 2020
The evolvability of lead peptides from small library screens
Jinglei Zhang1, Berea A R Williams, Mikael T Nilsson
1Center for Evolutionary Medicine and Informatics at the Biodesign Institute, Arizona State University, Tempe, AZ 85287-5301, USA.
Abstract:
Very little is known about the evolvability of lead peptides that are isolated from small library screens. Here we begin to explore this question by comparing the directed evolution of two peptides previously isolated from a small library screen to new ligands generated de novo by in vitro selection.

