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Updated: Jun 8, 2026
07:17
Single Port Donor Nephrectomy
Published on: March 12, 2011
Risk factors for delayed graft function after hand-assisted laparoscopic donor nephrectomy.
R C Minnee1, W A Bemelman, K A M I Donselaar-van der Pant
1Department of Surgery, Academic Medical Center, Amsterdam, the Netherlands. rcminnee@hotmail.com
Transplantation Proceedings
|September 14, 2010
Summary
Delayed graft function (DGF) in kidney transplants is linked to multiple renal veins in donors and acute rejection in recipients. Identifying these risk factors can improve transplant outcomes.
Area of Science:
- Nephrology
- Transplant Surgery
- Medical Research
Background:
- Delayed graft function (DGF) negatively impacts living-donor kidney transplant outcomes.
- Understanding DGF is crucial for improving graft survival rates.
Purpose of the Study:
- To identify and analyze potential risk factors associated with DGF in living-donor kidney transplantation.
- To investigate both donor and recipient factors contributing to DGF.
Main Methods:
- Prospective study of 200 living donor-recipient pairs from January 2002 to July 2007.
- DGF defined as the need for dialysis within the first postoperative week.
- Multivariate analysis to determine independent risk factors.
Main Results:
- DGF occurred in 6% of patients, significantly reducing one-year graft survival (52% vs. 98%).
- Univariate donor risk factors included lower scintigraphy counts and multiple renal veins.
- Multivariate analysis identified multiple renal veins and acute rejection episodes as independent risk factors for DGF.
Conclusions:
- Hand-assisted laparoscopic donor nephrectomy is a safe procedure.
- Multiple renal veins in donors and acute rejection episodes in recipients are significant independent risk factors for DGF.
- Identifying these factors can guide strategies to mitigate DGF and enhance transplant success.
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