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Related Concept Videos

Preventive Healthcare Services01:30

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase01:11

Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...
Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...

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Related Experiment Video

Updated: Jun 8, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

Targeting risk groups for screening.

Jaroslaw Regula1, Michal F Kaminski

  • 1Department of Gastroenterology and Hepatology, Medical Center for Postgraduate Education, Warsaw, Poland. jregula@coi.waw.pl

Best Practice & Research. Clinical Gastroenterology
|September 14, 2010
PubMed
Summary
This summary is machine-generated.

Personalizing colorectal cancer (CRC) screening using individual risk factors like gender and race could improve early detection. However, this approach may complicate current screening guidelines for patients and doctors.

Related Experiment Videos

Last Updated: Jun 8, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

Area of Science:

  • Oncology
  • Preventive Medicine
  • Public Health

Background:

  • Current colorectal cancer (CRC) screening guidelines primarily rely on age and family history.
  • Individual risk factors beyond age and family history are not extensively utilized in CRC screening protocols.

Purpose of the Study:

  • To explore the potential of customizing colorectal cancer (CRC) screening based on a wider range of individual risk factors.
  • To identify modifiable factors for personalized CRC screening strategies.

Main Methods:

  • Review of existing colorectal cancer (CRC) screening guidelines.
  • Analysis of potential risk factors including gender, race, ethnicity, lifestyle, and comorbidities.
  • Evaluation of the feasibility of incorporating these factors into screening protocols.

Main Results:

  • Factors such as gender, race, ethnicity, smoking, obesity, diabetes, and metabolic syndrome could inform personalized CRC screening.
  • Modifiable aspects include screening test choice, initiation age, and screening intervals.
  • Inclusion of race in guidelines has already begun for specific populations (e.g., African-Americans).

Conclusions:

  • Personalized colorectal cancer (CRC) screening offers potential benefits for early detection and resource optimization.
  • Integrating multiple risk factors may enhance screening effectiveness.
  • A significant challenge is the potential for increased complexity, impacting patient and physician understanding of guidelines.