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07:22
Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells
Published on: March 28, 2013
pRb, a switch between bone and brown fat
Pablo J Fernandez-Marcos1, Johan Auwerx
1Laboratory for Integrative and Systems Physiology, Ecole Polytechnique Fédérale de Lausanne, CH1015 Lausanne, Switzerland.
Developmental Cell
|September 14, 2010
Abstract:
Calo et al. (2010) recently reported that the absence of the transcriptional regulator pRb enhances differentiation of mesenchymal precursors toward the brown adipocyte lineage in detriment of osteoblast and white fat populations. These findings may have therapeutic implications for cancer and bone and metabolic disease.
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