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Updated: Jun 8, 2026

Adipo-Clear: A Tissue Clearing Method for Three-Dimensional Imaging of Adipose Tissue
Published on: July 28, 2018
Three-dimensional radiofrequency tissue tightening: a proposed mechanism and applications for body contouring
Malcolm Paul1, G Blugerman, M Kreindel
1Department of Surgery, Aesthetic and Plastic Surgery Institute, University of California, Irvine, CA 92697, USA. mpaulmd@hotmail.com
Abstract:
The use of radiofrequency energy to produce collagen matrix contraction is presented. Controlling the depth of energy delivery, the power applied, the target skin temperature, and the duration of application of energy at various soft tissue levels produces soft tissue contraction, which is measurable. This technology allows precise soft tissue modeling at multiple levels to enhance the result achieved over traditional suction-assisted lipectomy as well as other forms of energy such as ultrasonic and laser-generated lipolysis.

