Components of convolvulin from Quamoclit × multifida

Area of Science:

• Phytochemistry
• Natural Product Chemistry
• Organic Chemistry

Background:

• Seeds of Quamoclit × multifida (Convolvulaceae) contain complex resin glycosides.
• Convolvulin is a major ether-insoluble fraction known for its glycosidic components.

Purpose of the Study:

• To isolate and characterize novel glycosidic acids from Quamoclit × multifida seeds.
• To identify the full spectrum of acidic compounds present in the convolvulin fraction.

Main Methods:

• Alkaline hydrolysis of the ether-insoluble resin glycoside fraction.
• Spectroscopic analysis (e.g., NMR, MS) for structural elucidation.
• Chemical derivatization and evidence for structural confirmation.

Main Results:

• Isolation of three new glycosidic acids: maltifidinic acids C, D, and E.
• Identification of three known glycosidic acids: quamoclinic acids B, C, and D.
• Detection of four known organic acids: 2S-methylbutyric, tiglic, 2R,3R-nilic, and 7S-hydroxydecanoic acids.

Conclusions:

• The convolvulin fraction of Quamoclit × multifida seeds is a rich source of diverse glycosidic and organic acids.
• The structures of the novel maltifidinic acids were successfully elucidated.
• This research expands the known chemical profile of Quamoclit × multifida.