COMT Val158Met polymorphism, cognitive stability and cognitive flexibility: an experimental examination.

Elise C Rosa1, Dwight Dickinson, José Apud

  • 1Clinical Brain Disorders Branch, National Institute of Mental Heath/National Institutes of Health, 10 Center Drive, MSC 1379, Bethesda, MD 20892, USA.

Summary

The Catechol-O-Methyltransferase (COMT) Val158Met polymorphism influences cognitive processes. Met allele carriers showed an advantage in cognitive stability tasks, but the COMT Val/Met effect was not observed for cognitive flexibility.

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