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Updated: Jun 8, 2026

Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
Published on: December 22, 2023
[Overlooked Wolff-Parkinson-White syndrome]
Trine Skov Nielsen1, Søren Dalager, Maiken Kudahl Larsen
1Aarhus Universitet, Retsmedicinsk Institut, Arhus, Denmark. skovtrine@hotmail.com
Abstract:
An autopsy in a 28-year-old man did not explain the cause of sudden unexpected death. However, a history of episodes with tachycardia and dizziness and a reassessed previous electrocardiogram exhibiting ventricular pre-excitation was consistent with Wolff-Parkinson-White (WPW) syndrome. In this patient we believe that the occurrence of atrial fibrillation caused sudden cardiac death from ventricular fibrillation due to a short refractory period of an accessory atrioventricular pathway and a very rapid ventricular rate in atrial fibrillation.
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