Related Experiment Video
Updated: Jun 8, 2026

Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles
Published on: January 22, 2015
Preparation and characterization of water-soluble chitosan derivative by Michael addition reaction
Mingyan Jiang1, Kemin Wang, John F Kennedy
1Changzhou University, Changzhou 213164, PR China.
Abstract:
The efficient procedure to prepare novel water-soluble chitosan derivative was established by Michael addition reaction to introduce sodium allylsulfonate into the chitosan at mild condition. The chemical structure of the chitosan derivative was characterized by FT-IR, (1)H NMR and Elemental analysis. The degree of substitution (DS) was calculated by Elemental analysis. The chitosan derivative exhibited an excellent solubility in the distilled water. The physical properties were analyzed by XRD and TG. The XRD study indicated that the crystallinity of chitosan derivative decreased. The thermal analysis showed that chitosan derivative had lower thermal stability than chitosan.
More Related Videos
Related Concept Videos
Conjugate Addition of Enolates: Michael Addition
Preparation of Alcohols via Addition Reactions
The acid-catalyzed addition of water to the double bond of alkenes is a large-scale industrial method used to synthesize low-molecular-weight alcohols. An acidic atmosphere is required to allow the hydrogen in the water molecule to act as an electrophile and attack the double bond in an alkene. The addition of a proton to the double bond creates a carbocation intermediate. The proton preferentially bonds to the less substituted end of the double bond to create a more stable carbocation...
Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration
Cyclohexenones via Michael Addition and Aldol Condensation: The Robinson Annulation
Preparation and Reactions of Thiols
Preparation and Reactions of Sulfides

