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Dandy-Walker malformation: An incidental finding

Jyothi Tadakamadla1, Santhosh Kumar, G P Mamatha

  • 1Department of Oral Medicine and Radiology, Darshan Dental College and Hospital, Udaipur-313 001, Rajasthan, India.

Indian Journal of Human Genetics
|September 15, 2010
PubMed

Keywords:
Dandy–Walkerhigh arch palatehypertelorism

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Nondisjunction

During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.