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Major arterial aneurysms and pseudoaneurysms in Behçet's disease: results from a single centre

S B Cho1, T Kim, S Cho

  • 1Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.

Scandinavian Journal of Rheumatology
|September 16, 2010
PubMed

Insights

Behçet

Area of Science:

  • Vascular Medicine
  • Rheumatology
  • Immunology

Background:

  • Behçet's disease (BD) significantly increases mortality and morbidity due to arterial complications like occlusion and aneurysm rupture.
  • Early identification and characterization of arterial aneurysms in BD are crucial for managing severe outcomes.

Purpose of the Study:

  • To investigate the clinical features of Behçet's disease patients presenting with aneurysms and pseudoaneurysms in major arteries.
  • To analyze the characteristics, treatment responses, and recurrence rates of arterial aneurysms in BD.

Main Methods:

  • Retrospective review of medical records for 30 Behçet's disease patients with diagnosed arterial aneurysms or pseudoaneurysms.
  • Data collected included patient demographics, aneurysm/pseudoaneurysm characteristics, laboratory findings, and treatment outcomes.

Main Results:

  • 47 aneurysms/pseudoaneurysms were identified in 30 patients; 90% were unruptured.
  • Symptomatic lesions occurred in 70% of patients; 33.3% had multiple lesions.
  • Recurrence was noted in 16.7% of patients post-treatment.

Conclusions:

  • Behçet's disease patients with major arterial aneurysms require thorough evaluation for associated thrombosis or additional aneurysmal lesions.
  • Comprehensive assessment is vital for optimal management and prevention of complications in BD-related arterial disease.
Abstract

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