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Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pain01:20

Pain

Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
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Related Experiment Video

Updated: Jun 8, 2026

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams
09:00

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams

Published on: July 7, 2023

Pediatric pain management knowledge linkages: mapping experiential knowledge to explicit knowledge.

Sam Stewart1, Syed Sibte Raza Abidi, Allen Finley

  • 1Faculty of Computer Science, Dalhousie University, Halifax, Canada. sam.stewart@dal.ca

Studies in Health Technology and Informatics
|September 16, 2010
PubMed
Summary
This summary is machine-generated.

This project connects clinician discussions on pediatric pain to evidence-based research. It enhances communication by linking practical experience with scientific literature for better child pain management.

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Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
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Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

Related Experiment Videos

Last Updated: Jun 8, 2026

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams
09:00

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams

Published on: July 7, 2023

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

Area of Science:

  • Medical Informatics
  • Pediatric Pain Management
  • Clinical Communication

Background:

  • Clinician communication relies heavily on shared experiential knowledge.
  • Tacit knowledge in pediatric pain management is often shared through forums like the Pediatric Pain Mailing List (PPML).
  • Bridging experiential knowledge with evidence-based research is crucial for improving clinical practice.

Purpose of the Study:

  • To augment clinician communication by integrating evidence-based research with shared experiential knowledge.
  • To create a system that connects discussions from the Pediatric Pain Mailing List (PPML) to relevant medical literature.
  • To provide healthcare practitioners with easily accessible, research-backed information to support clinical decision-making in pediatric pain.

Main Methods:

  • Processing historical messages from the Pediatric Pain Mailing List (PPML) into organized threads.
  • Parsing message content and assigning Medical Subject Headings (MeSH) keywords.
  • Utilizing MeSH keywords to search PubMed and retrieve corresponding research papers.
  • Presenting archived discussions and linked literature in an online forum.

Main Results:

  • A system for connecting informal clinician discussions to formal medical literature has been developed.
  • The system successfully links archived Pediatric Pain Mailing List (PPML) conversations to relevant PubMed articles.
  • An online platform is available for clinicians to explore past discussions and supporting research.

Conclusions:

  • Connecting experiential knowledge from clinician forums with evidence-based research can significantly enhance communication and practice in pediatric pain management.
  • The developed system provides a valuable resource for healthcare practitioners seeking to integrate research findings into their clinical work.
  • This approach facilitates a more informed and collaborative approach to addressing challenges in pediatric pain.