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Related Experiment Video

Updated: Jun 8, 2026

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Weight loss maintenance.

Samuel N Grief¹, Rosita L F Miranda

¹University of Illinois at Chicago (UIC), Department of Family Medicine, Chicago, Illinois 60612, USA. sgrief@uic.edu

American Family Physician

|September 17, 2010

Summary

This summary is machine-generated.

Achieving long-term weight loss maintenance involves lifestyle changes like diet, exercise, and behavioral strategies. Medical interventions, including pharmacotherapy and bariatric surgery, offer additional options for sustained weight management.

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Area of Science:

Obesity research
Weight management strategies
Metabolic health

Background:

Long-term weight loss maintenance is a significant challenge for many individuals.
The National Weight Control Registry highlights the success of combined dietary, physical activity, and behavioral interventions.
Adherence to consistent weight loss regimens remains a key limitation.

Purpose of the Study:

To review various successful approaches for long-term weight loss maintenance.
To evaluate the efficacy of pharmacologic treatments and bariatric surgery for sustained weight management.
To identify key factors contributing to successful weight loss maintenance.

Main Methods:

Review of established weight loss maintenance strategies, including behavioral and lifestyle modifications.
Analysis of long-term pharmacologic treatments for weight loss, noting modest success and typical weight regain.
Examination of bariatric surgery as a modality for significant weight loss and maintenance in severe obesity.

Main Results:

Combination of diet, physical activity, and behavioral support aids weight loss maintenance but requires adherence.
Pharmacologic treatments (e.g., sibutramine, orlistat) show modest success with some weight regain.
Bariatric surgery demonstrates significant success in weight loss, maintenance, and comorbid condition remission for morbidly obese patients.

Conclusions:

Successful long-term weight loss maintenance can be achieved through a combination of lifestyle interventions and professional support.
Pharmacologic and surgical interventions offer viable options for specific patient populations.
Sustained weight management requires ongoing commitment to chosen strategies, whether behavioral, medical, or surgical.