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Harnessing transposons for cancer gene discovery

Neal G Copeland1, Nancy A Jenkins

  • 1Genomics and Genetics Division, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, 61 Biopolis Drive, Proteos, Singapore 138673.

Nature Reviews. Cancer
|September 17, 2010
PubMed
Summary

The Sleeping Beauty (SB) transposon system enables cancer gene discovery in mice. This technology identifies known and novel cancer genes and pathways driving tumor formation, aiding in potential drug target identification.

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