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Gender differences on chest pain perception associated with acute myocardial infarction in Chinese patients: a
Jane J B Khan1, John W Albarran, Violet Lopez
1The Cardiac Care Center, The Queen Elizabeth Hospital, Kowloon, Hong Kong, China. janekhan@netvigator.com
Insights
Chinese men and women exhibit distinct chest pain perceptions during acute myocardial infarction. Women, presenting with more atypical symptoms, represent a high-risk group for delayed diagnosis and require aggressive investigation.
Area of Science:
- Cardiology
- Medical Research
- Clinical Diagnostics
Background:
- Timely treatment of acute myocardial infarction (AMI) is crucial, with thrombolytic therapy most effective within 12 hours of chest pain onset.
- Patient interpretation of cardiac symptoms can delay hospital presentation.
- Gender-based differences in symptom reporting may contribute to misdiagnoses and treatment delays, particularly for women.
Purpose of the Study:
- To investigate gender-specific differences in chest pain perception among Chinese patients experiencing acute myocardial infarction.
- To determine if established trends of atypical symptom presentation in women with AMI apply to the Chinese population.
Main Methods:
- A descriptive prospective study design was employed.
- Data collected via questionnaires included demographics, prevalence of chest pain and other sensations, pain intensity, description, location, and radiation.
- 128 participants, equally divided by gender, were recruited.
Main Results:
- Chest pain was reported more frequently by men (84.37%) than women (67.19%).
- Men experienced more upper right chest pain (40.74% vs. 20.93%), while women reported increased neck and central chest/back pain.
- Women were more likely to report atypical chest pain (9.3% vs. 0.00%).
Conclusions:
- Significant gender disparities in chest pain perception exist in Chinese AMI patients.
- Women with AMI in this cohort presented with more atypical symptoms, highlighting them as a high-risk group for delayed diagnosis.
- Aggressive investigation is warranted for women presenting with potential myocardial infarction symptoms, regardless of cultural background.
Aims:
To investigate gender differences in chest pain perception among Chinese patients with acute myocardial infarction.
Background:
Thrombolytic therapy is beneficial to outcomes of acute myocardial infarction if administered within 12 hours from the onset of chest pain. However, cardiac symptom interpretation may impact time of presentation to hospital. Differences in cardiac symptom reports by gender partly explain misdiagnoses and delays in treatment, particularly among women. Whether, such trends apply to Chinese patients with myocardial infarction is unknown.
Design:
A descriptive prospective study.
Methods:
Using questionnaires, data on demographic variables, the number of patients reporting chest pain and other chest sensations at the onset of acute myocardial infarction and chest pain intensity, description, location and radiation across the chest were collected.
Results:
A total of 128 participants equally divided by gender were recruited. Chest pain was more prevalent among men than women (84.37% vs. 67.19%, p < 0.05). Although no statistical significance was found, Chinese men had higher mean chest pain intensity scores (7.54 SD 2.35 vs. 7.51 SD 2.25) and reported less atypical chest pain (0.00% vs. 9.3%) compared with women. Men had more upper right sided chest pain (40.74% vs. 20.93%, p = 0.038) whereas women experienced increased neck pain and pain to the upper central chest, middle central chest, upper central back, middle central back and middle right back regions.
Conclusions:
Discreet gender differences in chest pain perceptions exist between Chinese men and women, with the latter group, who may be considered as a high-risk group for missed and delayed diagnosis from myocardial infarction, reporting more atypical presentations.
Relevance To Clinical Practice:
Irrespective of culture, women with myocardial infarction tend to present with atypical chest pain symptoms and therefore they should be aggressively investigated.
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