Laryngeal juvenile xanthogranuloma: Imaging finding

Area of Science:

• Pediatric Otolaryngology
• Diagnostic Imaging
• Pathology

Background:

• Juvenile xanthogranuloma (JXG) is a rare histiocytic disorder, typically affecting the skin and eyes.
• Laryngeal involvement is exceptionally uncommon, with only four prior English literature reports.
• This study details a unique case of isolated JXG in the supraglottic region of the larynx.

Observation:

• Ultrasonography revealed a well-defined, homogeneous hypoechoic mass.
• Computed Tomography (CT) demonstrated an indistinct boundary with soft tissue density.
• Radiological findings were nonspecific, necessitating correlation with clinical presentation.

Findings:

• The case presented as an isolated JXG of the larynx.
• Imaging characteristics, while nonspecific, helped delineate the lesion's extent.
• The patient's symptoms, including laryngeal stridor, were associated with the JXG.

Implications:

• JXG should be considered in the differential diagnosis of pediatric laryngeal stridor.
• Laryngeal ultrasound is a safe, reliable tool for evaluating laryngeal masses.
• Ultrasound can supplement traditional laryngoscopy in diagnosing laryngeal lesions like JXG.