Use of analgesics and antibiotics in endodontics: current concepts

In this review, the principal drugs used for prevention and treatment of pain--analgesics, and swelling--antibiotics, are examined. The rationale for prevention of pain and swelling is given. Then the specific drugs are considered. The analgesics evaluated include: the non-steroidal anti-inflammatory agents (e.g., aspirin, acetaminophen, ibuprofen, diflunisal); and the narcotics (e.g., codeine, oxycodone, hydrocodone, meperidine). The antibiotics evaluated include: the penicillins (e.g., penicillin V, ampicillin, methicillin); the cephalosporins (e.g., cephalexin, cefadroxil); the erythromycins (e.g., erythromycin stearate, erythromycin base); clindamycin; metronidazole; and some rarely used drugs (e.g., ciprofloxacin).