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Total synthesis of berkelic acid

Thomas N Snaddon1, Philipp Buchgraber, Saskia Schulthoff

  • 1Max-Planck-Institut für Kohlenforschung, 45470 Mülheim/Ruhr, Germany.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|September 21, 2010
PubMed
Summary

This study details a novel total synthesis for both enantiomers of berkelic acid, a bioactive fungal metabolite. The efficient route utilizes a cascade reaction to construct the tetracyclic core, confirming a revised structure.

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