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Updated: Jun 8, 2026

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A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Complications of mandibular distraction osteogenesis
Daniel L Master1, Pamela R Hanson, Arun K Gosain
1Department of Orthopedic Surgery, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
The Journal of Craniofacial Surgery
|September 22, 2010
Summary
Mandibular distraction osteogenesis (MDO) is a surgical technique for correcting jaw deformities, but it can lead to complications like relapse and tooth injury. Careful planning and technique are crucial to avoid these issues.
Area of Science:
- Pediatric Plastic Surgery
- Craniofacial Surgery
- Surgical Complications
Background:
- Mandibular hypoplasia, retrognathia, and micrognathia are common pediatric plastic surgery concerns.
- Mandibular distraction osteogenesis (MDO) offers a solution for these deformities with low morbidity.
- However, MDO is associated with various potential complications.
Purpose of the Study:
- To review and compile complications associated with Mandibular Distraction Osteogenesis (MDO).
- To present case reports illustrating MDO complications.
- To inform surgical planning and technique to mitigate MDO risks.
Main Methods:
- A comprehensive PubMed database search was conducted for articles detailing MDO complications.
- Relevant data from identified articles were extracted and systematically compiled.
- Illustrative case reports were included to highlight specific complications.
Main Results:
- The most frequent complication of MDO is relapse, with an incidence of 64.8%.
- Other significant complications include tooth injury (22.5%), hypertrophic scarring (15.6%), and nerve injury (11.4%).
- Less common complications involve infection, distraction vector errors, device failure, fusion errors, and temporomandibular joint injury.
Conclusions:
- Mandibular distraction osteogenesis (MDO) is linked to a range of complications, both minor and major.
- Meticulous surgical planning and precise technique are essential for preventing MDO-related complications.
- Adherence to best practices can significantly improve patient outcomes and minimize adverse events.
