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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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A 3D Organotypic Melanoma Spheroid Skin Model
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Giant melanoma: novel problem, same approach.

Andre D Grisham1

  • 1Department of Surgery, Baptist Memorial Hospital, Memphis, TN, USA. docag01@aol.com

Southern Medical Journal
|September 23, 2010
PubMed
Summary
This summary is machine-generated.

Giant melanomas, over 10 cm, are rare but managed with standard wide surgical excision. Sentinel lymph node biopsy is recommended for staging in cases without apparent metastasis.

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Area of Science:

  • Dermatology
  • Surgical Oncology

Background:

  • Thick melanomas are frequently diagnosed.
  • Melanomas exceeding 10 cm in diameter are exceptionally rare.

Observation:

  • Despite their large size, the diagnostic and therapeutic principles for giant melanomas are consistent with smaller thick melanomas.

Findings:

  • Standard workup and wide surgical excision are the recommended treatments for melanomas >10 cm.
  • Sentinel lymph node biopsy is a crucial staging procedure for patients with no clinical signs of metastasis.

Implications:

  • This approach ensures appropriate management for rare, large melanomas.
  • Early staging via sentinel lymph node biopsy can guide adjuvant therapy decisions.