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Related Experiment Video

Updated: Jun 8, 2026

Ratiometric Imaging of Extracellular pH in Dental Biofilms

Ratiometric Imaging of Extracellular pH in Dental Biofilms

Published on: March 9, 2016

In vivo acid etching effect on bacteria within caries-affected dentin.

F Gu¹, E Bresciani, T J Barata

¹School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA.

Caries Research

|September 24, 2010

Summary

This summary is machine-generated.

Acid etching minimally invasive caries treatment did not significantly alter bacterial counts. However, it may inhibit the activity of remaining cariogenic bacteria, suggesting potential benefits for dental restorations.

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Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Published on: March 31, 2021

Area of Science:

Dentistry
Microbiology
Biomaterials

Background:

Minimally invasive caries removal aims to preserve tooth structure.
Acid etching is used in adhesive dentistry to improve bond strength.
The effect of acid etching on residual bacteria in caries lesions is not fully understood.

Purpose of the Study:

To evaluate the in vivo effect of acid etching on cariogenic bacterial activity in dentin after selective caries removal.
To compare bacterial counts and activity between acid-etched and non-etched groups post-restoration.

Main Methods:

Twenty-eight carious teeth underwent selective caries removal.
Teeth were randomly assigned to acid etch (E) or no etch (NE) treatment before adhesive restoration.
Dentin biopsies were collected at baseline and 3 months for bacterial quantification and activity assessment using qPCR and RT-PCR.

Main Results:

No significant differences in total bacterial number or activity were found between the E and NE groups.
In the NE group, residual Streptococcus mutans counts decreased, but activity per cell increased significantly at 3 months.
This increase in bacterial activity was not observed in the acid-etched (E) group.

Conclusions:

Acid etching prior to adhesive restoration may have an inhibitory effect on the activity of residual cariogenic bacteria.
While not statistically significant between groups, the findings suggest a potential benefit of acid etching in managing bacterial activity post-treatment.
Further research is needed to confirm the direct or indirect inhibitory mechanisms of acid etching on cariogenic bacteria.