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Updated: Jun 8, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
[Infection of mycobacterium tuberculosis in lung cancer.]
1Department of Respiratory Diseases , Affiliated Hospital of Bengbu Medical College , Bengbu , Anhui 233004 , P. R. China.
Background:
To investigate the relationship between pulmonary tuberculosis and lung cancer.
Methods:
A prospective study on the infection of mycobacterium tuberculosis was carried out in 330 lung cancer patients by classic acid-fast staining (ZN) and improved acid-fast staining ( IK) method and immunohistochemistry staining (ABC) and TB-PCR methods.
Results:
Positive rate of mycobacterium tuberculosis by ZN was 27. 88 % in the specimens from fiber bronchoscopic brash of 330 patients with lung cancer ; the rate by IKand ABC was 38. 71 % and 51. 61 % respectively in 93 cancer tissue specimens , and 57. 14 % for mycobacterium tuberculosis cultivation in 14 dissected cancer tissue specimens and 60 % for TB-PCR in 20 tumor samples.
Conclusions:
There is high infection rate of mycobacterium tuberculosis in lung cancer patients , especially its L-form. These results suggest that there might be a relationship between pulmonary tuberculosis and lung cancer.
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