Random-walk mechanism in the genetic recombination
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Updated: Jun 8, 2026

Molecular Evolution of the Tre Recombinase
Published on: May 29, 2008
Youhei Fujitani1, Junji Kawai, Ichizo Kobayashi
1Keio University, 223-8522 Yokohama, Japan. youhei@appi.keio.ac.jp
Abstract:
We have explained some experimental data of the homologous recombination and the genetic interference in terms of one-dimensional random walk over discrete sites. We first review our previous results. Next, we modify our random-walk model for the homologous recombination into a continuous-site model, and discuss a possible explanation for the previous experimental data obtained by means of the plasmid having one-side homology. Finally, we show that a reaction between an intermediate and a product is indispensable in explaining the genetic interference in terms of our reaction-diffusion model.
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