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Related Concept Videos

Antifungal Agents01:15

Antifungal Agents

Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...
Psychosis: Goals of Pharmacotherapy01:26

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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
Candidiasis01:20

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Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
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Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

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Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Hand hygiene01:23

Hand hygiene

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Related Experiment Video

Updated: Jun 8, 2026

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians
06:49

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians

Published on: March 14, 2014

Onychomycosis therapy: past, present, future.

Aditya K Gupta1, Michael Uro, Elizabeth A Cooper

  • 1Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Center, University of Toronto, Toronto, Canada. agupta@execulink.com

Journal of Drugs in Dermatology : JDD
|September 28, 2010
PubMed
Summary
This summary is machine-generated.

New device-related topical therapies show promise for treating onychomycosis (fungal nail infection), offering alternatives to oral medications with potential safety and compliance benefits.

Related Experiment Videos

Last Updated: Jun 8, 2026

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians
06:49

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians

Published on: March 14, 2014

Area of Science:

  • Dermatology
  • Mycology
  • Medical Technology

Background:

  • Onychomycosis treatment traditionally relies on topical and oral therapies.
  • Oral antifungal agents are considered the gold standard but have limitations in efficacy and safety.
  • Patient adherence to long-term topical treatments can be challenging.

Observation:

  • Advancements in topical therapies are improving nail penetration and treatment efficacy.
  • Device-related topical therapies, including light-based methods, are emerging as innovative treatment options.
  • These novel approaches aim to enhance patient convenience and reduce adverse drug reactions.

Findings:

  • New topical and device-related therapies are being explored to overcome limitations of current onychomycosis treatments.
  • Device-assisted topical treatments may offer shorter, more manageable treatment durations.
  • Non-drug, light-based therapies present an alternative to avoid potential drug interactions or side effects.

Implications:

  • Further research is needed to establish the long-term impact and clinical utility of these emerging therapies.
  • Device-related topical treatments could significantly improve patient compliance and treatment outcomes for onychomycosis.
  • These innovations may reshape the future landscape of fungal nail infection management.