Related Experiment Video
Updated: Jun 8, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
[Computer simulations of electrical activity of the heart]
Abstract:
Computer simulations of electrical activity in the heart involve three levels of complexity: simulations of a single cardiocyte, a slab of tissue and the whole organ. For each of the levels there are both conceptual mathematical models to describe the common features of the dynamics, and detailed models to estimate parameters with the precision comparable to that obtained in the experiment. I consider modern approaches and provide examples of simulations; the accent is on simulations of action potential and membrane currents.
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