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Related Concept Videos

Trichomoniasis01:18

Trichomoniasis

Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.
Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
Microbiota of the Urogenital Tract01:28

Microbiota of the Urogenital Tract

The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...
Vagina01:26

Vagina

The vaginal canal is a tubular structure averaging about 10 cm in length that acts as the entryway to the female reproductive system and the passageway for menstrual flow and childbirth. The interior walls of the vagina exhibit concentric folds called rugae and are topped by an area known as the fornix, which connects with the protruding cervical portion of the uterus. This canal is comprised of an external fibrous layer, a muscular middle layer, and an inner lining with mucosal rugae, which...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

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Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria
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Atrophic vaginitis.

Catherine S Stika1

  • 1Department of Obstetrics & Gynecology, Northwestern University, Feinberg School of Medicine, 680 North Lake Shore Drive, Chicago, IL60611, USA. c-stika@northwestern.edu

Dermatologic Therapy
|September 28, 2010
PubMed
Summary

Menopause causes vulvovaginal atrophy, leading to debilitating symptoms in many women. Topical estrogen therapies and vaginal moisturizers effectively treat these menopausal changes and associated symptoms.

Area of Science:

  • Gynecology
  • Menopause research
  • Vaginal health

Background:

  • Menopause leads to estrogen loss, causing vulvovaginal mucosal changes.
  • Atrophic vaginitis affects 10-47% of postmenopausal women with debilitating symptoms.
  • Symptoms include dryness, pain during intercourse, itching, recurrent UTIs, and discharge.

Purpose of the Study:

  • To review the effects of menopause on vulvovaginal health.
  • To discuss the efficacy of treatments for atrophic vaginitis.

Main Methods:

  • Literature review on menopausal changes and treatment outcomes.
  • Analysis of studies on topical estrogen therapies, moisturizers, and lubricants.

Main Results:

  • Topical estrogen replacement therapies effectively reverse mucosal changes.

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  • Vaginal moisturizers and lubricants offer symptomatic relief for dryness and dyspareunia.
  • Conclusions:

    • Atrophic vaginitis is a common consequence of menopause-related estrogen loss.
    • Topical estrogen and supportive therapies are effective management options for symptom relief.