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Updated: Jun 8, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Does a 3-sip test detect dysphagia in acute stroke rehabilitation patients?
Stephanie A Kopey1, John Chae, Mary M Vargo
1Metrohealth Rehabilitation Institute of Ohio, Case Western Reserve University 2500 Metrohealth Dr, Cleveland, OH 44109, USA. sp135901@ohio.edu
Objectives:
(1) Evaluate sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of a 3-sip test within 24 hours of acute stroke as a screening for clinically relevant dysphagia during acute rehabilitation. (2) For those patients who pass the 3-sip test, identify factors predictive of later detection of clinically relevant dysphagia.
Design:
A retrospective review.
Setting:
Acute stroke rehabilitation unit of a tertiary academic medical center.
Patients:
223 patients undergoing dysphagia screening after stroke.
Main Outcome Measure:
Development of clinically relevant dysphagia.
Results:
Seventeen of 223 patients (7.6%) failed the 3-sip test. Of the 206 patients who passed the 3-sip test, 57 (27.7%) manifested clinically relevant dysphagia. Sensitivity and specificity of the 3-sip test were 20.8% and 98.7%, respectively. PPV and NPV were 88.2% and 72.3%, respectively. Among those who passed the 3-sip test, logistic regression identified the Functional Independence Measure (FIM) total score as the only independent predictor (B = -0.066, P < .001) of clinically relevant dysphagia. Of those patients who passed the 3-sip test, 54.6% with an FIM total score <60 had clinically relevant dysphagia compared with 11.9% with an FIM total score >60.
Conclusions:
The sensitivity of the 3-sip test was poor for stroke rehabilitation patients. For those who passed the 3-sip test, a low FIM total score was predictive of development of clinically relevant dysphagia. A high degree of clinical suspicion for dysphagia should remain after passing a 3-sip screening test, especially for those with FIM total score <60.
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