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Updated: Jun 8, 2026

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
Published on: July 25, 2013
SimiCon: a web tool for protein-ligand model comparison through calculation of equivalent atomic contacts
Manuel Rueda1, Vsevolod Katritch, Eugene Raush
1UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California-San Diego, La Jolla, CA 92093, USA.
Summary:
SimiCon is a web server designed for an automated identification of equivalent protein-ligand atomic contacts in different conformational models of a complex. The contacts are computed with internal coordinate mechanics (ICM) software with respect to molecular symmetry and the results are shown in the browser as text, tables and interactive 3D graphics. The web server can be executed remotely without a browser to allow users to automate multiple calculations.
Availability:
SimiCon is freely available at http://abagyan.ucsd.edu/SimiCon
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