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Threshold to elicit seizures by picrotoxin is lowered in pentylenetetrazol-kindled mice
G Grecksch1, A Becker, H Matthies
1Institute for Pharmacology and Toxicology, Medical Academy Magdeburg, GDR.
Neuropharmacology
|November 1, 1990
Abstract:
The convulsant effect of different doses of picrotoxin was investigated in pentylenetetrazol-kindled and saline-treated mice. The percentage of convulsions was greater in the kindled mice, compared to controls.