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Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
Neuronal Communication01:28

Neuronal Communication

Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
Neural Circuits01:25

Neural Circuits

Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
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Action Potential01:14

Action Potential

Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Propagation of Action Potentials01:23

Propagation of Action Potentials

The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...

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Related Experiment Video

Updated: Jun 8, 2026

In Vivo Visualization of Spontaneous Activity in Neonatal Mouse Sensory Cortex at a Single-Neuron Resolution
06:18

In Vivo Visualization of Spontaneous Activity in Neonatal Mouse Sensory Cortex at a Single-Neuron Resolution

Published on: November 21, 2023

[Spontaneous activity of the developing neuronal networks].

M G Sheroziia, A V Egorov

    Zhurnal Vysshei Nervnoi Deiatelnosti Imeni I P Pavlova
    |September 29, 2010
    PubMed
    Summary

    Early spontaneous network activity in the developing nervous system, observed in the brain and spinal cord, is crucial for neuronal growth and network construction during maturation.

    Area of Science:

    • Neuroscience
    • Developmental Biology

    Context:

    • Spontaneous periodic network activity is a hallmark of the developing nervous system.
    • This early neural activity occurs in various regions, including the hippocampus, cortex, retina, and spinal cord, in embryonic and newborn animals.

    Purpose:

    • To review principal studies on spontaneous network activity in the developing nervous system.
    • To discuss potential mechanisms underlying the generation of this activity.

    Summary:

    • The review examines spontaneous periodic network activity, a key feature of neural development.
    • This activity is thought to influence neuronal growth and network formation during brain maturation.
    • Studies in multiple embryonic and newborn nervous system regions are discussed.

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    Functional Calcium Imaging in Developing Cortical Networks
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    Functional Calcium Imaging in Developing Cortical Networks

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    Assessment of the Effects of Endocrine Disrupting Compounds on the Development of Vertebrate Neural Network Function Using Multi-electrode Arrays
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    Assessment of the Effects of Endocrine Disrupting Compounds on the Development of Vertebrate Neural Network Function Using Multi-electrode Arrays

    Published on: April 26, 2018

    Related Experiment Videos

    Last Updated: Jun 8, 2026

    In Vivo Visualization of Spontaneous Activity in Neonatal Mouse Sensory Cortex at a Single-Neuron Resolution
    06:18

    In Vivo Visualization of Spontaneous Activity in Neonatal Mouse Sensory Cortex at a Single-Neuron Resolution

    Published on: November 21, 2023

    Functional Calcium Imaging in Developing Cortical Networks
    16:33

    Functional Calcium Imaging in Developing Cortical Networks

    Published on: October 22, 2011

    Assessment of the Effects of Endocrine Disrupting Compounds on the Development of Vertebrate Neural Network Function Using Multi-electrode Arrays
    08:28

    Assessment of the Effects of Endocrine Disrupting Compounds on the Development of Vertebrate Neural Network Function Using Multi-electrode Arrays

    Published on: April 26, 2018

    Impact:

    • Highlights the fundamental role of early neural network activity in brain development.
    • Provides insights into the mechanisms driving neural maturation.
    • Serves as a foundational resource for researchers studying neurodevelopment.