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Updated: Jun 8, 2026

Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method
Published on: May 12, 2023
[Quality control of traditional Tibetan Medicine Zsuotai]
Zhen-jiang Xia1, Li-xin Wei, Dong-ping Wang
1Northwest Plateau Institute of Biology, Chinese Academy of Sciences/Qinghai Key Laboratory of Tibet Medicine Pharmacology and Satety Evaluation, Xining 810008, China. xiazhenjiang6184@163.com
Objective:
To establish the method of quality control for traditional Tibetan Medicine Zsuotai.
Methods:
Collecting the samples of Tsuotai from Qinghai, Tibet, Sichuan, and Gansu province, to detect Hg2+ by Zsuotai reacted with HCl-HNO3 (3:1), and to determine the quantity of HgS in Zsuotai by sulfocyanate volumetric method.
Results:
The method for the determination of HgS in Zsuotai was in good reproducibility (RSD = 0.68%). The calibration curve was linear (r = 0.9999) within -0.0002 - 0.2123 g of mercuric sulfide. The recovery was 100.94% (RSD = 0.66%).
Conclusions:
This method is convenient and accurate, so it can be used to establish quality control of the medicinal material.
