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Updated: Jun 8, 2026

In Vitro Model of Coronary Angiogenesis
Published on: March 10, 2020
Angiogenesis and the heart
Shree G Sharma1, Sudip Nanda, Santo Longo
1Department of Pathology, University of Arkansas, Arkansas, USA. drshreegopal@gmail.com
Insights
Cardiovascular disease is rising globally. This review explores new angiogenesis treatments and patents for cardiac patients lacking other options.
Area of Science:
- Cardiovascular Medicine
- Regenerative Medicine
- Biotechnology
Background:
- Global incidence of cardiovascular disease is increasing.
- Many cardiac patients are unsuitable for current treatments, creating a 'no-option' subgroup.
- This subgroup drives innovation in cardiac angiogenesis therapies.
Purpose of the Study:
- To review current treatment modalities for cardiac angiogenesis in 'no-option' patients.
- To discuss patents filed to advance cardiac angiogenesis.
- To highlight the importance of developing new therapies for this patient population.
Main Methods:
- Literature review of treatment modalities for cardiac angiogenesis.
- Analysis of filed patents related to cardiac angiogenesis.
- Synthesis of information on therapeutic approaches and intellectual property.
Main Results:
- Several treatment modalities are being explored for cardiac angiogenesis.
- Numerous patents have been filed, indicating significant research and development activity.
- The field of cardiac angiogenesis is rapidly evolving in response to unmet clinical needs.
Conclusions:
- Angiogenesis offers a promising therapeutic avenue for 'no-option' cardiovascular patients.
- Ongoing research and patent filings underscore the potential of this field.
- Further development is crucial to translate these advancements into clinical practice.
Abstract:
The incidence of cardiovascular disease is increasing worldwide. Despite many new developments in 60(th) medical and surgical specialities, a substantial number of cardiac patients are not suitable candidates for one of the current treatment options. This "no-option" subgroup of patients is a driving influence in the rapidly developing field of angiogenesis. In this review, we discuss the different modalities of treatment being tried for these patients and the patents which have been filed to improve cardiac angiogenesis.
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