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Updated: Jun 8, 2026

Rectal Organoid Morphology Analysis (ROMA): A Diagnostic Assay in Cystic Fibrosis
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Rectal Organoid Morphology Analysis (ROMA): A Diagnostic Assay in Cystic Fibrosis

Published on: June 10, 2022

Rowell's syndrome.

M L Khatri1

  • 1Department of Dermatology, Saudi Hospital at Hajjah, Yemen.

Indian Journal of Dermatology, Venereology and Leprology
|September 30, 2010
PubMed
Summary
This summary is machine-generated.

This case study highlights a patient with systemic lupus erythematosus (SLE) who experienced recurrent erythema multiforme-like rashes. The findings strongly suggest the presence of Rowell's syndrome, a rare condition linking lupus and specific skin manifestations.

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Last Updated: Jun 8, 2026

Rectal Organoid Morphology Analysis (ROMA): A Diagnostic Assay in Cystic Fibrosis
07:56

Rectal Organoid Morphology Analysis (ROMA): A Diagnostic Assay in Cystic Fibrosis

Published on: June 10, 2022

Area of Science:

  • Dermatology
  • Rheumatology
  • Internal Medicine

Background:

  • Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical presentations.
  • Rowell's syndrome is a rare condition characterized by lupus erythematosus and characteristic skin findings, including erythema multiforme.
  • Cutaneous manifestations in SLE can be varied and sometimes overlap with other dermatological conditions.

Purpose of the Study:

  • To report a case of recurrent erythema multiforme-like eruption in a patient with systemic lupus erythematosus.
  • To investigate the potential association with Rowell's syndrome.
  • To contribute to the understanding of rare SLE-associated dermatological conditions.

Main Methods:

  • Clinical case presentation and detailed patient history.
  • Review of laboratory findings, including complete blood count, autoimmune markers, and urinalysis.
  • Assessment of clinical features against diagnostic criteria for Rowell's syndrome.

Main Results:

  • A 22-year-old female patient presented with recurrent erythema multiforme-like skin eruptions.
  • Laboratory results revealed leucopenia, anaemia, a positive LE cell phenomenon, positive rheumatoid factor, and mild proteinuria.
  • The patient's clinical presentation met most criteria for Rowell's syndrome.

Conclusions:

  • The presented case strongly indicates Rowell's syndrome in a patient with systemic lupus erythematosus.
  • Recurrent erythema multiforme-like eruptions can be a significant cutaneous manifestation of SLE.
  • Recognition of Rowell's syndrome is crucial for comprehensive patient management in rheumatology and dermatology.