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Updated: Jun 8, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Spontaneous rupture of a functioning adrenocortical carcinoma
Jin Ook Chung1, Dong Hyeok Cho, Jae Hyuk Lee
1Department of Internal Medicine, Chonnam National University Medical School, Dong-gu, Gwangju, Korea.
Abstract:
Adrenocortical carcinoma (ACC) is a rare malignancy with poor prognosis, and it can be classified as either a functional or nonfunctional tumor. Affected patients usually present with abdominal pain or with symptoms related to the mass effect or hormonal activity of the tumor. Several cases of spontaneously ruptured nonfunctional adrenocortical carcinoma have been reported, but no case of a spontaneous rupture of functioning adrenocortical carcinoma has been described. We report a functioning adrenocortical carcinoma that spontaneously ruptured during a work-up.
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