Related Experiment Video
Updated: Jun 8, 2026
Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
Published on: April 9, 2019
Evaluation of inter-session 3D-TRUS to 3D-TRUS image registration for repeat prostate biopsies
Vaishali V Karnik1, Aaron Fenster, Jeff Bax
1Biomedical Engineering Graduate Program, The University of Western Ontario, London, ON, Canada N6A 5C1.
Abstract:
To ensure accurate targeting and repeatability, 3D TRUS-guided biopsies require registration to determine coordinate transformations to (1) incorporate pre-procedure biopsy plans and (2) compensate for inter-session prostate motion and deformation between repeat biopsy sessions. We evaluated prostate surface- and image-based 3D-to-3D TRUS registration by measuring the TRE of manually marked, corresponding, intrinsic fiducials in the whole gland and peripheral zone, and also evaluated the error anisotropy. The image-based rigid and non-rigid methods yielded the best results with mean TREs of 2.26 mm and 1.96 mm, respectively. These results compare favorably with a clinical need for an error of less than 2.5 mm.
