Activity-dependent dendritic secretion of brain-derived neurotrophic factor modulates synaptic plasticity

Nicola Kuczewski1, Christophe Porcher, Jean-Luc Gaiarsa

  • 1INMED (Institut de Neurobiologie de la Méditerranée), INSERM (Institut National de la Santé et de la Recherche Médicale Unité 901), Marseille, France.

Summary

Brain-derived neurotrophic factor (BDNF) release from neurons shapes neural circuits. Recent findings highlight how activity-dependent dendritic BDNF secretion specifically impacts synapse efficacy and development.

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