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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
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Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

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[(18)F]2-fluoro-2-deoxy-D-glucose PET/CT in mediastinal masses.

S Rankin1

  • 1Department of Radiology, Guy's Hospital, St Thomas Street, London, UK. sheila.rankin@gstt.nhs.uk

Cancer Imaging : the Official Publication of the International Cancer Imaging Society
|October 1, 2010
PubMed
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Computed tomography (CT) and magnetic resonance imaging (MRI) help locate mediastinal masses. However, [(18)F]fluorodeoxyglucose-positron emission tomography/CT offers advanced characterization for residual tumors and biopsy guidance.

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Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT)
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Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT)

Published on: May 2, 2012

Area of Science:

  • Radiology
  • Nuclear Medicine
  • Oncology

Background:

  • Computed tomography (CT) and magnetic resonance imaging (MRI) are standard for localizing mediastinal masses.
  • These imaging techniques often provide diagnostic features but have limitations in assessing tumor aggressiveness or viability.
  • Residual masses after chemotherapy pose challenges for evaluating tumor response.

Purpose of the Study:

  • To evaluate the role of metabolic imaging in characterizing mediastinal masses.
  • To determine the utility of [(18)F]fluorodeoxyglucose-positron emission tomography/CT (FDG-PET/CT) in assessing tumor aggressiveness and residual disease.
  • To explore FDG-PET/CT's potential in guiding biopsy site selection.

Main Methods:

  • Review of CT and MRI findings in mediastinal masses.
  • Analysis of FDG-PET/CT scans for metabolic activity and characterization of masses.
  • Correlation of imaging findings with clinical outcomes and histopathology where available.

Main Results:

  • CT and MRI effectively localize mediastinal masses and suggest diagnoses.
  • Assessing mass aggressiveness and viable tumor in residual masses is challenging with CT/MRI alone.
  • FDG-PET/CT provides additional metabolic information, aiding in further characterization and biopsy guidance.

Conclusions:

  • While CT and MRI are valuable for mediastinal mass localization, FDG-PET/CT offers complementary information.
  • Metabolic imaging with FDG-PET/CT can enhance the characterization of mediastinal masses, particularly in assessing tumor viability.
  • FDG-PET/CT may be beneficial for guiding biopsy in complex cases, improving diagnostic accuracy.