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Reference values for the Nocturnal Bladder Capacity Index.

Claire Burton1, Jeffrey P Weiss, Matthew Parsons

  • 1Department of Urogynaecology, Birmingham Women's Hospital, Birmingham, UK.

Neurourology and Urodynamics
|October 1, 2010
PubMed
Summary
This summary is machine-generated.

The unrounded Nocturnal Bladder Capacity Index (NBCi) is more sensitive for detecting low nocturnal bladder capacity in women with LUTS. An unrounded NBCi of 1.3 is a recommended cutoff for investigating nocturia causes.

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Area of Science:

  • Urology
  • Nephrology
  • Gerontology

Background:

  • Nocturia is a common condition affecting quality of life.
  • The Nocturnal Bladder Capacity Index (NBCi) aids in differentiating causes of nocturia.
  • Distinguishing low bladder capacity from nocturnal polyuria is crucial for effective treatment.

Purpose of the Study:

  • Establish reference values for the NBCi in an asymptomatic population.
  • Compare NBCi values between asymptomatic individuals and female patients with LUTS.
  • Evaluate the sensitivity of the NBCi in detecting reduced nocturnal bladder capacity.
  • Compare the accuracy of rounded versus unrounded NBCi calculations.

Main Methods:

  • Analysis of 3-day bladder diaries from 253 asymptomatic volunteers and 184 female LUTS patients.
  • Calculation of NBCi using both rounded and unrounded formulae.
  • Determination of 90th and 95th centile cutoff values from frequency distributions.

Main Results:

  • Unrounded NBCi reference values (95th centile) were 1.3; rounded values were 1.0.
  • The unrounded formula showed continuous variation with V(n)/V(max) ratios, unlike the rounded formula.
  • The unrounded formula identified significantly more elevated NBCi values in the patient group.

Conclusions:

  • An unrounded NBCi cutoff of 1.3 is proposed for investigating reduced nocturnal bladder capacity as a cause of nocturia.
  • Rounding the NBCi underestimates elevated values in female patients with LUTS.
  • The unrounded NBCi calculation is more sensitive for detecting reduced nocturnal bladder capacity.