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Updated: Jun 8, 2026

Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes
Published on: April 1, 2013
Dual fluorescent N-aryl-2,3- naphthalimides: applications in ratiometric DNA detection and white organic
Premchendar Nandhikonda1, Michael D Heagy
1Department of Chemistry, New Mexico Institute of Mining and Technology, Socorro, New Mexico 87801, United States.
Abstract:
A ten element matrix of 5- and 6-substituted-(2,3)-naphthalimides was prepared for the appropriate placement of substituents necessary to promote dual fluorescence (DF). As prescribed by our balanced seesaw photophysical model this matrix yielded nine new DF dyes out of a possible ten compounds. From this set of nine DF dyes, 4-fluoronaphthalic amide (37) was selected as a probe for ratiometric detection of DNA and demonstration of panchromatic emission.

