Inositol hexakisphosphate kinases promote autophagy

Eiichiro Nagata1, Adolfo Saiardi, Hideo Tsukamoto

  • 1Department of Neurology, Tokai University School of Medicine, 143 Shimo-Kasuya, Isehara, Kanagawa 259-1193, Japan.

Summary

Inositol hexakisphosphate kinases (InsP(6)Ks) promote autophagy and increase cell death. This study reveals InsP(6)Ks induce caspase-independent cell death, opening new autophagy pathways.

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