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Ruptured intracranial mycotic aneurysm in infective endocarditis: a natural history
Isabel Kuo1, Theodore Long, Nathan Nguyen
1University of Southern California Keck School of Medicine, Los Angeles, CA 90089, USA.
Abstract:
Mycotic aneurysms are a rare cause of intracranial aneurysms that develop in the presence of infections such as infective endocarditis. They account for a small percentage of all intracranial aneurysms and carry a high-mortality rate when ruptured. The authors report a case of a 54-year-old man who presented with infective endocarditis of the mitral valve and acute stroke. He subsequently developed subarachnoid hemorrhage during antibiotic treatment, and a large intracranial aneurysm was discovered on CT Angiography. His lesion quickly progressed into an intraparenchymal hemorrhage, requiring emergent craniotomy and aneurysm clipping. Current recommendations on the management of intracranial Mycotic Aneurysms are based on few retrospective case studies. The natural history of the patient's ruptured aneurysm is presented, as well as a literature review on the management and available treatment modalities.
Insights
Mycotic aneurysms, rare brain artery bulges caused by infection, have high mortality if ruptured. This case highlights emergent treatment for a ruptured mycotic aneurysm in a patient with infective endocarditis.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Surgery
Background:
- Mycotic aneurysms are uncommon intracranial aneurysms associated with infections like infective endocarditis.
- Ruptured mycotic aneurysms have a high mortality rate.
Observation:
- A 54-year-old male with mitral valve infective endocarditis and acute stroke developed subarachnoid hemorrhage.
- CT Angiography revealed a large intracranial aneurysm, which rapidly progressed to intraparenchymal hemorrhage.
Findings:
- The patient required emergency craniotomy and aneurysm clipping for the ruptured lesion.
- Management guidelines for intracranial mycotic aneurysms are limited, often based on retrospective studies.
Implications:
- This case underscores the critical, rapid progression of ruptured mycotic aneurysms.
- Presents a patient's natural history and reviews current management strategies for these rare vascular lesions.
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