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Related Experiment Video

Updated: Jun 8, 2026

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

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Published on: July 11, 2025

Cost-effectiveness of colonoscopy.

¹Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, 307 East 63rd Street, Room 357, New York, NY 10065, USA. zaubera@mskcc.org

Gastrointestinal Endoscopy Clinics of North America

|October 5, 2010

Summary

This summary is machine-generated.

Multiple colorectal cancer screening strategies, including colonoscopy and sensitive fecal occult blood tests, are cost-effective. Annual sensitive FOBTs and flexible sigmoidoscopy with FOBT are recommended for early detection and prevention.

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Published on: August 1, 2019

Area of Science:

Health Economics
Preventive Medicine
Gastroenterology

Background:

Colorectal cancer (CRC) screening guidelines recommend multiple strategies.
Assessing the cost-effectiveness of these recommended strategies is crucial for healthcare resource allocation.

Purpose of the Study:

To perform a cost-effectiveness analysis of CRC screening tests recommended by major US guideline groups.
To identify which recommended screening strategies are cost-effective across various willingness-to-pay thresholds.

Main Methods:

Cost-effectiveness analysis of recommended colorectal cancer screening tests.
Evaluation based on willingness to pay per life-year gained.

Main Results:

Annual sensitive fecal occult blood tests (FOBTs), including guaiac and fecal immunochemical tests (but not Hemoccult II), are cost-effective for early cancer detection.
Flexible sigmoidoscopy every 5 years combined with frequent sensitive FOBT is cost-effective for cancer prevention.
Colonoscopy is also identified as a cost-effective strategy.
Computed tomographic colonography was not found to be cost-effective.

Conclusions:

Multiple colorectal cancer screening strategies, including colonoscopy and specific FOBT-based approaches, are cost-effective.
The choice of screening strategy can be guided by cost-effectiveness alongside clinical recommendations.
Sensitive FOBTs and combined sigmoidoscopy/FOBT represent valuable options for CRC screening and prevention.