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Related Experiment Video

Updated: Jun 8, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

Primary hyperparathyroidism presenting as intractable nausea and vomiting.

Chen Ming-Kai¹, Zhou Ting

¹Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan City, HuBei Province, People's Republic of China. Kaimingchen@163.com

Southern Medical Journal

|October 5, 2010

Summary

This summary is machine-generated.

Primary hyperparathyroidism (PHPT) can present with atypical symptoms like palpitations or nausea, even with normal initial calcium levels. This case highlights the importance of considering PHPT in elderly women with non-specific complaints.

Related Experiment Videos

Last Updated: Jun 8, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

Area of Science:

Endocrinology
Geriatric Medicine

Background:

Primary hyperparathyroidism (PHPT) involves excessive parathyroid hormone (PTH) secretion.
An increasing number of PHPT cases are asymptomatic or present with atypical symptoms.
PHPT commonly affects elderly women, often with subtle or absent complications.

Observation:

A 77-year-old woman with undiagnosed PHPT initially presented with palpitations and chest distress.
Subsequent symptoms included intractable nausea and vomiting.
Initial lab tests showed normal calcium levels, but further examination revealed elevated serum calcium and PTH.

Findings:

The case demonstrates that PHPT can manifest with non-specific gastrointestinal and cardiovascular symptoms.
Elevated PTH and calcium levels confirmed the diagnosis despite initially normal calcium.
Literature review emphasized the diagnostic challenge of PHPT in asymptomatic or atypically presenting patients.

Implications:

Highlights the need for heightened clinical suspicion for PHPT in elderly patients with non-specific symptoms.
Underscores the importance of comprehensive biochemical evaluation, including PTH and calcium levels, for PHPT diagnosis.
Informs treatment strategies for PHPT in the elderly, considering the unique challenges in this demographic.