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A role for hypocretin/orexin in motivation

Jennifer L Thompson1, Stephanie L Borgland

  • 1Department of Anesthesiology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.

Behavioural Brain Research
|October 6, 2010
PubMed
Summary

Hypocretin/orexin (Hcrt/ox) neurons promote effort for rewards by acting on dopamine pathways. This highlights a key mechanism in motivated behaviors like obesity and drug addiction.

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