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Related Concept Videos

Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...

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Retrograde Tracing of Drosophila Embryonic Motor Neurons Using Lipophilic Fluorescent Dyes
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Acropigmentation of dohi.

R R Mittal1,

  • 1Department of Dematology & Venereology, Government Medical College, Rajindra Hospital, Patiala - 147001, Punjab, India.

Indian Journal of Dermatology, Venereology and Leprology
|October 6, 2010
PubMed
Summary

Acropigmentation of Dohi, a rare skin condition, presents as distinct hypo- and hyperpigmented macules on the extremities. These lesions in two pediatric cases stabilized after initial development, offering insights into its natural course.

Area of Science:

  • Dermatology
  • Genetics
  • Pediatric Medicine

Background:

  • Acropigmentation of Dohi is a rare genodermatosis characterized by reticulated hyperpigmentation and hypopigmentation.
  • It typically presents in childhood with lesions predominantly on the dorsal aspects of the hands and feet.

Purpose of the Study:

  • To report two pediatric cases of Acropigmentation of Dohi.
  • To describe the clinical presentation and progression of the condition in these patients.

Main Methods:

  • Case report methodology was employed.
  • Clinical observations of skin lesions on the hands and feet were documented.

Main Results:

  • Two cases, a 9-year-old boy and an 8-year-old girl, were identified.

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  • Both patients exhibited hypopigmented macules interspersed with brownish macules on the dorsa of their hands and feet.
  • Lesions demonstrated stability after an initial period of progression.

    • Conclusions:

    • Acropigmentation of Dohi can present in childhood with characteristic macular patterns.
    • The condition appears to stabilize over time, suggesting a self-limiting or slowly progressive course in pediatric cases.