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Peripheral T-lymphocyte counts in seborrhoeic keratosis.

R R Mittal¹, Jindal Sonal¹

¹Department of Dermatovenereology, Govt.Medical College & Rajendra Hospital, Patiala - 147001, Punjab, India.

Indian Journal of Dermatology, Venereology and Leprology

|June 16, 2017

Summary

Seborrhoeic keratosis and stucco keratosis show increased T-lymphocyte counts, indicating a significant role for cell-mediated immunity in these skin conditions. This finding highlights the immune system

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Area of Science:

Dermatology
Immunology

Background:

Seborrhoeic keratosis and stucco keratosis are common skin conditions.
The role of cell-mediated immunity in these conditions requires further investigation.

Purpose of the Study:

To investigate the T-lymphocyte counts in patients with clinically diagnosed seborrhoeic keratosis and stucco keratosis.
To determine the association between T-lymphocyte levels and these skin conditions.

Main Methods:

Histopathological confirmation of 148 cases of seborrhoeic keratosis and 12 cases of stucco keratosis.
Peripheral T-lymphocyte counts were determined using Thomson's E-rosette method (1977).

Main Results:

Histopathology confirmed 123 cases of seborrhoeic keratosis and 8 cases of stucco keratosis.
Peripheral T-lymphocyte counts were statistically significantly increased in both seborrhoeic keratosis and stucco keratosis patients.
The findings suggest a significant role for cell-mediated immunity in seborrhoeic keratosis.

Conclusions:

Cell-mediated immunity plays a significant role in the pathogenesis of seborrhoeic keratosis.
Increased T-lymphocyte counts are observed in both seborrhoeic keratosis and stucco keratosis.